The Oxfam Homeware store on Arnold high street is closing.
The outlet is one of two shops run by the charity in the town.
But this week Oxfam’s head office said that they could not afford to keep it running.
The charity shop chain raises money to reduce global poverty.
An Oxfam spokesperson said: “Oxfam shops exist to raise as much money as possible to overcome poverty and suffering in some of the poorest countries in the world.
“We constantly evaluate the profitability of all our shops, to ensure they are efficient and making the most money for Oxfam’s vital work.
“Sometimes this leads to difficult decisions about the viability of particular shops.
“These decisions are never taken lightly and we always take into account the impact on our staff and volunteers.
“We have made the difficult decision to close the Oxfam homewares store on Nottingham Road, Arnold, on Friday, May 19.
“However, the Oxfam store on Front Street will remain open and customers can continue to support us there as they have done so generously over the years.”
Residents of Arnold took to social media to speculate the charity shop’s apparent closure.
One wrote: “Hopefully it will not be another bar or fast food shop”, with another hoping for the location to become an arts and craft shop.
